Louisville, KY - Cane Run Rd
SAM's Chicago Grill - Louisville's Boldest Flavors
Louisville's boldest flavors - wings, cheesesteaks, catfish & more. Fried fresh daily on Cane Run Rd.
The Story
SAM's Chicago Grill brings the bold, authentic flavors of the Windy City straight to Cane Run Road in Louisville. We're not just serving food - we're serving a Chicago tradition built on slow-simmered Italian beef, snappy all-beef Chicago dogs, and the kind of no-nonsense flavors that made the Second City famous.
Our Italian Beef is the real deal: thinly sliced, perfectly seasoned beef slow-cooked in rich au jus, piled high on a fresh hoagie roll with sweet or hot peppers. Get it dipped for the full Chicago experience. Our Chicago Dog? A Vienna all-beef frank on a poppy seed bun, loaded with yellow mustard, chopped onions, bright green relish, tomato wedges, sport peppers, a pickle spear, and a dash of celery salt - dragged through the garden, just like they do it back home.
But we don't stop at Chicago classics. Our kitchen also fires up hand-battered Traditional Bone-In Wings, golden-fried catfish, loaded Philly cheesesteaks, and crispy chicken tenders - all made fresh daily with the same commitment to quality and flavor. Wash it all down with Lady J's Lemonade, the perfect tart-sweet refresher for a hot Louisville day.
Whether you're a Chicago native craving a taste of home or a Louisville local ready to experience something bold and authentic, SAM's Chicago Grill is here for you. Proudly serving Louisville, Shively, Valley Station, Pleasure Ridge Park, and the entire Jefferson County area.
Got Questions?
What meals do you serve?
SAM's Chicago Grill in Louisville serves a bold menu blending Mexican cuisine with American comfort food favorites. Our crispy Traditional Bone-In Wings come seasoned, battered, and fried fresh daily with your choice of flavor and fries. Seafood lovers enjoy our golden-fried Catfish Fillets and Catfish Nuggets, made fresh every day. Our Original Philly Cheesesteak on a fresh hoagie bun is loaded with grilled onions, peppers, and melted mozzarella-provolone. Wash it all down with Lady J's refreshing homemade Lemonade, perfect for any casual dining occasion.
Do you offer delivery or takeout?
Yes, we offer both delivery and pickup. Order conveniently online or by phone.
Where are you located?
SAM's Chicago Grill is located at 4501 Cane Run Rd, Louisville, KY 40216.
What areas do you serve?
SAM's Chicago Grill proudly serves Louisville and surrounding neighborhoods including Shively, Valley Station, Pleasure Ridge Park, Dixie Highway, Portland, Iroquois, Beechmont, Fairdale, Okolona, and the greater Jefferson County area.
Find Us / Hit Us Up
Address
4501 Cane Run Rd
Louisville, KY 40216
Phone
Ordering
Delivery & Pickup Available
Hungry? Don't wait. Place your order online and we'll have your food ready - fresh, hot, and packed with flavor. Delivery straight to your door or pick it up on Cane Run Rd.
Order Now